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How is this perilla leaf oil extracted, and which method is preferred?

Perilla leaf oil is produced by three validated methods; steam distillation is the standard, while supercritical CO2 extraction yields the highest perillaldehyde recovery.

Extraction Methods

MethodProcessKey Advantage
Steam distillation (standard)Fresh leaves & aerial parts steam-distilled per ChP 2025 Volatile Oil Determination (通则 2204)Most economical; classic green-minty perilla profile
Ultrasonic + freeze-drying + supercritical CO2 (CN201110304608)Ultrasonic cell-wall disruption (20–25 KHz, 10–20 min) → freeze (-20 to -25°C, 6 h) → vacuum freeze-drying → SFE-CO2 (30–40 MPa, 40–50°C)Perillaldehyde extraction rate up to 92%; zero solvent residue; preserves heat-sensitive actives
Low-temperature steam distillation + molecular distillationTwo-stage low-temperature distillation; monoterpene retention 89.3%Higher purity perillaketone 98.2%; impurities ≤ 0.18%; ISO 22000 & EU EC 1831/2003 certified
  • For flavor and food applications the low-temperature + molecular distillation line is preferred — it protects volatile monoterpenes and meets food-safety certification
  • For fine perfumery, SFE-CO2 material is preferred when a richer, more complete top-note profile is required
  • Every batch ships with a GC-MS chromatogram identifying up to 97 compounds (ISO 11024-1/2 method)

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This article was published on 2026-09-07, and last updated on 2026-09-07. The article will be continuously updated.