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How do you ensure batch-to-batch consistency of Chuanxiong rhizome oil?

Consistency is controlled by standardized raw material, fixed process parameters, and multi-point QC on every batch.

Consistency Controls

ControlMethod
Raw materialDao-di rhizome sourcing, moisture and marker pre-screening
GC-MS fingerprintISO 11024 method; profile similarity ≥90% vs. reference
HPLC markersLigustilide and ferulic acid quantified on every batch
Physical testsDensity, refractive index, optical rotation per batch
Chemical testsAcid value, ester value per batch
Retained samples24-month retention for re-test and complaint verification
  • Suggested internal control: adopt HPLC fingerprinting as a routine batch-consistency check in addition to classic parameters
  • Reported batch variation is typically within ±10% relative for the main phthalides
  • Annual production review correlates markers with harvest quality for continuous improvement

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This article was published on 2026-09-07, and last updated on 2026-09-07. The article will be continuously updated.