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What are the key aromatic and active compounds in this Angelica root oil?

The oil is characterized by phthalides, with ligustilide 45–65% as the core marker, plus senkyunolide A, butylphthalide (≥18%), ferulic acid, Dang Gui polysaccharides and alpha-pinene; more than 52 components are identified by GC-MS.

Key Compounds

CompoundTypical levelRole
Ligustilide (Z/E)45–65%Signature aroma + TRPV1-modulating active
Butylphthalide (n-butylidene phthalide)≥18%Warm spicy depth, functional marker
Senkyunolide APresentPhthalide freshness, TCM quality marker
Ferulic acidTrace–lowAntioxidant co-marker (T/CACM 1021.1)
Dang Gui polysaccharidesIn extract/CO2 formBioactive fraction (cosmetic & nutra use)
Alpha-pinene & minor terpenesBalanceFresh green top lift
  • Z-ligustilide retention ≥91.7% in supercritical CO2 batches — the heat-sensitive isomer most valued in TCM and cosmetics
  • Phthalides show bidirectional modulation of the TRPV1 receptor (2023 Chinese Journal of Chinese Materia Medica), supporting the warming-comfort positioning
  • Refined batches carry coefficient of variation (CV) below 4.7% across the main markers

Request the GC-MS chromatogram and marker report with your COA.

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This article was published on 2026-09-07, and last updated on 2026-09-07. The article will be continuously updated.