What are the key aromatic and active compounds in this Angelica root oil?
The oil is characterized by phthalides, with ligustilide 45–65% as the core marker, plus senkyunolide A, butylphthalide (≥18%), ferulic acid, Dang Gui polysaccharides and alpha-pinene; more than 52 components are identified by GC-MS.
Key Compounds
| Compound | Typical level | Role |
|---|---|---|
| Ligustilide (Z/E) | 45–65% | Signature aroma + TRPV1-modulating active |
| Butylphthalide (n-butylidene phthalide) | ≥18% | Warm spicy depth, functional marker |
| Senkyunolide A | Present | Phthalide freshness, TCM quality marker |
| Ferulic acid | Trace–low | Antioxidant co-marker (T/CACM 1021.1) |
| Dang Gui polysaccharides | In extract/CO2 form | Bioactive fraction (cosmetic & nutra use) |
| Alpha-pinene & minor terpenes | Balance | Fresh green top lift |
- Z-ligustilide retention ≥91.7% in supercritical CO2 batches — the heat-sensitive isomer most valued in TCM and cosmetics
- Phthalides show bidirectional modulation of the TRPV1 receptor (2023 Chinese Journal of Chinese Materia Medica), supporting the warming-comfort positioning
- Refined batches carry coefficient of variation (CV) below 4.7% across the main markers
Request the GC-MS chromatogram and marker report with your COA.
This article was published on 2026-09-07, and last updated on 2026-09-07. The article will be continuously updated.