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How is this Angelica root oil extracted, and which method is preferred?

The oil is produced by classic steam distillation or supercritical CO2 extraction of dried Dang Gui roots; supercritical CO2 preserves heat-sensitive phthalides and is the mainstream high-end route.

Extraction Details

ItemDetail
MethodSteam distillation / supercritical CO2 extraction
Raw materialDried Dang Gui roots (water ≤13%, milled 24–60 mesh)
Steam distillation~0.4% yield; 6× water, ~7 h (optimized per 2022 research)
Supercritical CO230–40°C, 28–32 MPa, oxygen-free; Z-ligustilide retention ≥91.7%
Subcritical HFC-134aPatented route CN102911783A: 2.0% yield, ligustilide 62.16%
RefiningTriple refining: first distillation → middle fraction (185–210°C) → short-path molecular distillation
  • Steam distillation keeps the product 100% solvent-free for aromatherapy and cosmetic-grade claims
  • Supercritical CO2 extraction (used by ~93% of China's Dang Gui oil producers) protects the heat-sensitive ligustilide isomers and raises yield several-fold
  • Patented low-temperature processes (CN102911783A, CN121914813A) retain phthalide actives such as senkyunolide A and butylphthalide
  • Every batch is verified by GC-MS fingerprinting before release

For your target application we can match the extraction route (plain steam distillation, CO2 or combined) to your specification.

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This article was published on 2026-09-07, and last updated on 2026-09-07. The article will be continuously updated.